UK, 1851—a person (or persons) or a thing (or things) considered unattractive, inferior or unpleasant, compared to others of the same type or group—alludes to Cinderella’s ugly and unpleasant stepsisters in the fairy tale Cinderella
UK & USA, early 20th century—used in a variety of meanings, among which: ‘a postcard on which the sender could leave the imprint of a kiss’, and ‘a brief statement about kissing’
UK, 1951—‘mother-in-law’s chair’, ‘mother-in-law’s cushion’ and ‘mother-in-law’s seat’ are colloquial appellations for the globular spiny cactus Echinocactus grusonii, native to Mexico
looking or feeling ill or nauseated—1843, in a letter by Charles Dickens—when applied to a person, the plural noun ‘gills’ designates the flesh under the jaws and ears; also the cheeks